What it is
Selank was developed and registered in Russia as a nasal spray, so this is the format with the most direct research history. A synthetic tuftsin analogue with anxiolytic and nootropic activity in the literature.
Mechanism
Selank modulates GABAergic transmission, enkephalin metabolism and BDNF expression. Intranasal administration gives fast brain uptake; effects in studies begin within minutes.
Research areas
- Anxiety and stress models
- Cognitive function and learning
- Immunomodulation
- Intranasal peptide delivery
Safety and metabolism
Clinical use in Russia with a benign safety profile; no sedation or dependence reported.
